Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices

Keywords: fluoride varnish, casein phosphopeptide amorphous calcium phosphates, casein phosphopeptide amorphous calcium fluoride phosphates, tricalcium phosphate varnish, laser fluorescence, energy dispersive X-ray analysis

Abstract

Aim:  The goal of preventive dentistry is to intervene prior to the formation of dental caries. This study evaluated the remineralization effects of fluoride varnish, casein phosphopeptide amorphous calcium phosphates (CPP-ACP) and casein phosphopeptide amorphous calcium fluoride phosphates (CPP-ACFP) cream, and tricalcium phosphate (TCP) varnish.

Materials and Methodology: Samples with early artificial caries lesions were randomly divided into the following 5 groups with 20 samples in each group: (I) control, (II) fluoride varnish, (III) CPP-ACP cream, (IV) CPP-ACFP cream and (V) TCP varnish. The effectiveness of these remineralization agents was evaluated using a laser fluorescence device (DIAGNOdent), a scanning electron microscope (SEM) and energy dispersive X-ray analysis (EDX).

Results: In the pre- and post-treatment evaluations, the DIAGNOdent remineralization measurements were statistically significant in all the groups, except the control group (p < 0.05). In comparison with the DIAGNOdent measurements, the CPP-ACFP group was found to have significantly higher remineralization than the fluoride group (p < 0.05), while no significant differences were found between the other groups (p > 0.05). The EDX analysis evaluated the Ca/P ratio between the groups. These results indicated that the CPP-ACFP group was significantly higher than the control group, the CPP-ACP group and the TCP group (p < 0.05); no significant differences were found between the CPP-ACFP group and the fluoride group (p > 0.05). In SEM imaging, the most extensive mineral accumulation was observed in the CPP-ACFP group.

Conclusion: Three analytical methods demonstrated that CPP-ACFP was the most effective remineralization material tested in this study.

 

How to cite this article: Tatar E, Toptancı İR. Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. Int Dent Res 2019;9(3):138-44.

 

Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

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Published
2019-12-31
How to Cite
Tatar, E., & Toptancı, İsmet. (2019). Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. International Dental Research, 9(3), 138-144. https://doi.org/10.5577/intdentres.2019.vol9.no3.8