Comparison between Soft Gelatin Capsule Containing Ibuprofen and Ibuprofen Regular Tablet in Pain Control Following Scaling and Root Planing

Niloufar Jenabian(1), Ezzatollah Naderi(2), Ali-Akbar Moghadamnia(3), Samir Zahedpasha(4)
(1) Babol University of Medical Sciences, Faculty of Dentistry, Department of Periodontics, Babol, Iran, Iran, Islamic Republic of
(2) Babol University of Medical Sciences, Faculty of Dentistry, Babol, Iran, Iran, Islamic Republic of
(3) Babol University of Medical Sciences, Faculty of Medicine, Department of Pharmacology, Babol, Iran, Iran, Islamic Republic of
(4) Babol University of Medical Sciences, Faculty of Dentistry, Department of Endodontics, Babol, Iran, Iran, Islamic Republic of

Abstract

Aim: Scaling and root planing (SRP) is a major component of periodontal therapy which is often accompanied by painful experiences for the patient.  The objective of the present study is to evaluate the pain control of two available types of ibuprofen, soft gelatin capsules and tablets, following SRP in patients with chronic periodontitis.


Methodology: 75 patients with chronic periodontitis, undergoing routine periodontal SRP were selected. Following probing the amount of pain perceived was recorded as the baseline pain using visual analog scale (VAS). Further, they received either 800 mg ibuprofen tablet, 800 mg ibuprofen capsule or placebo and the pain level was measured thirty minutes thereafter. Participants underwent SRP procedure and the pain levels were recorded immediately and then at 30 and 60 minutes after SRP.


Results: The mean VAS pain scores assessed immediately, thirty minutes and an hour after SRP for both ibuprofen and ibuprofen capsule groups were lower than placebo. Significant difference in the pain parameter only immediately after SRP between three groups were observed (p=0.012).The mean VAS pain score difference after thirty minutes and an hour upon SRP with baseline was insignificant in all study groups (p≤0.0001). However, the mean VAS pain score measured an hour after SRP showed significant difference between both NSAID groups and placebo group (p=0.012)


Conclusions: Soft gelatin ibuprofen capsules are well suitable for pain management during SRP procedure in patients with chronic periodontitis due to reported rapid onset of action and less gastrointestinal intolerance. 


How to cite this article: Jenabian N, Naderi E, Moghadamnia AA, Zahedpasha S. Comparison between Soft Gelatin Capsule Containing Ibuprofen and Ibuprofen Regular Tablet in Pain Control Following Scaling and Root Planing. Int Dent Res 2011;2:42-47.


Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

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Authors

Niloufar Jenabian
Ezzatollah Naderi
Ali-Akbar Moghadamnia
Samir Zahedpasha
hakem3@dental-research.com (Primary Contact)
Jenabian, N., Naderi, E., Moghadamnia, A.-A., & Zahedpasha, S. (2011). Comparison between Soft Gelatin Capsule Containing Ibuprofen and Ibuprofen Regular Tablet in Pain Control Following Scaling and Root Planing. International Dental Research, 1(2), 42-47. https://doi.org/10.5577/intdentres.2011.vol1.no2.1

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How to Cite

Jenabian, N., Naderi, E., Moghadamnia, A.-A., & Zahedpasha, S. (2011). Comparison between Soft Gelatin Capsule Containing Ibuprofen and Ibuprofen Regular Tablet in Pain Control Following Scaling and Root Planing. International Dental Research, 1(2), 42-47. https://doi.org/10.5577/intdentres.2011.vol1.no2.1
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