Vol. 2 No. 1 (2012): Volume 2, No 1, 2012

Aim: The study was planned to assess the effect of a mouthrinse containing Chlorhexidine (CHX) and amine/stannous fluoride (AmF) on plaque accumulation, gingivitis and salivary fluoride levels in comparison with two mouthrinses containing either essential oils (EO) or cetylpyridinium chloride (CPC) with sodium fluoride (NaF) in a teenage group. Methodology: For this study 82 healthy teenage between 13 and 16 years were recruited for participation. The experimental gingivitis model consisted of a 2-weeks recruitment phase, followed by a 6-day rinsing period with one of the 4 mouthrinse formulations was used for the study. At the end of the pre-phase period and the rinsing period (Day-0/Day-6), gingival index (GI), plaque index (PI) and salivary fluoride levels were recorded. The statistical analyses were performed using Wilcoxon sign test  and the dependent t test. Results: A reduction in plaque re-growth was seen for the CHX+AmF formulation rinse, although there were no significant differences among all groups (p>0,001). During the experimental periods, the gingivitis indices increased significantly for all formulations (p<0,001), except for the CHX+AmF formulation. The CHX+AmF formulation scored higher levels of salivary fluoride at the end of the rinsing period (p>0,001). Conclusion: It reveals that the adjunctive use of AmF containing CHX mouthrinses to mechanical oral hygiene should be recommended for teenage at risk groups.  How to cite this article:  Atabek D, Alaçam A, Çakılcı B, Berkkan A. A Comparative Study of Fluoride Containing Chlorhexidine and Non-Chlorhexidine Mouthrinses in a Teenage Group. Int Dent Res 2012;1:1-7. Linguistic Revision:  The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

Aim: The aim of this immunohistochemical study was to assess the expression of angiogenic markers (vascular endothelial growth factor (VEGF) and microvessel density (MVD) in enamel matrix derivative (EMD) treated retromolar soft tissues to gain further insights into the biological mechanisms involved in wound healing and EMD treatment. Methodology: In twenty healthy volunteers, gingival biopsies were obtained from the distal wedge operations of test (EMD-applied) and control sites. EMD was applied into the test sites during the operation. At the 15th post-operative day, the sample sites were re-entered and gingival tissue samples were obtained from both test and control sites. A total of 80 samples for each sites were analyzed by immunohistochemistry for inflammatory infiltrate, expression of VEGF and MVD. Results: Despite similar post-operative inflammatory infiltrate, it was found that EMD- applied sites had statistically higher VEGF-A and VEGF-C expression and MVD compared to the controls on the 15th day. (p <0.0001 for each) Conclusions: This study supports that EMD has an angiogenic potential. The findings of this immunohistochemical analysis may help to gain insight into the angiogenic effects of EMD during the early phases of wound healing.  How to cite this article:  Özçelik O, Seydaoğlu G, Cömert M, Yılmaz E, Haytaç MC. Angiogenic Marker Alterations Following Enamel Matrix Derivative Treatment: A Human Study. Int Dent Res 2012;2:8-16. Linguistic Revision:  The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

The aim of this paper is to present the non-surgical management of three cases with large periapical lesions. Surgical treatment of large periapical lesions is often subject to various complications. Therefore, a non-surgical approach should be considered for the management of these lesions. The first was a maxillary lateral incisor with a periapical lesion of endodontic origin in a 19-year-old female patient, the second affected a maxillary central incisor in a 21-year-old female patient and the third was a mandibular molar in a 36-year-old male patient. The canals were prepared using crown down technique. During root canal treatment, sodium hypochlorite was used for irrigation and calcium hydroxide was used for the intra-canal dressing. Clinical evaluation was performed after 10 days. The teeth were asymptomatic and the root canals were obturated using lateral compaction technique. The patients were recalled at 3, 6 and 12 months. These radiolucent periapical lesions were treated successfully without surgical approach.  How to cite this article:  Arslan H, Karataş E, Barutcugil Ç, Topçuoğlu HS, Aladağ H. Treatment of Large Periapical Lesions without Surgical Approach: Report of Three Cases. Int Dent Res 2012;2:17-22 Linguistic Revision:  The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

Aim: Distraction osteogenesis (DO) is an alternative to orthognathic surgery that appears to have some advantages for advancement in the maxilla and mandible, but relatively high complication rates have been reported in the maxillofacial region. Methodology: A 22-year-old female with the chief complaint of maxillary hypoplasia was referred to our clinic. A two-stage procedure combining maxillary advancement by distraction technique with mandibular setback surgery was performed to correct jaw deformity. At the sixth day of the distraction breakage of the device occurred. The distractors were removed and the patient was treated using conventional osteotomy techniques to achieve good occlusion and improve the facial profile Results: Besides there are a number of studies about complications of DO, breakage of distractor has been really rare reported. In our case this unexpected and a very rarely reported complication occurred. Conclusions: The purpose of the present case report is to present an undesirable and very rare complication associated with the maxillary distraction device and an alternative treatment method for managing this undesirable failure. How to cite this article:  Apaydın A, Yenigün S, Can T. A Rare Complication Associated with Distraction Osteogenesis in Correction of Maxillary Hypoplasia. Int Dent Res 2012;2:23-26. Linguistic Revision:  The English in this manuscript has been checked by at least two professional editors, both native speakers of English.